Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA repair targeting and radiotherapy: a focus on the therapeutic ratio.

Seminars in radiation oncology - 1 Oct 2010

Thoms John, Bristow Robert G

Abstract excerpt

Radiotherapy (RT) results in the production of a variety of ionizing radiation-induced lesion in DNA. Specific pathways of DNA repair are required to repair the variety of lesions, which include DNA single-strand breaks (SSBs), DNA double-strand breaks (DSBs), DNA base alterations, and DNA-DNA or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clinical Trials as Topic
Share to DNA Breaks, Double-Stranded
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to DNA Repair

Share to Dose-Response Relationship, Radiation

Share to Precision Medicine

Share to Radiotherapy Dosage

Source

Identifiers

PMID: 20832013
DOI: 10.1016/j.semradonc.2010.06.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20832013-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA repair targeting and radiotherapy: a focus on the therapeutic ratio.PMID 20832013Read ↗

Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapySemantic proximity Read ↗

Altering DNA Repair to Improve Radiation Therapy: Specific and Multiple Pathway TargetingSemantic proximity Read ↗

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapySemantic proximity Read ↗

Ionizing Radiation-Induced DNA Damage, Response, and RepairSemantic proximity Read ↗

Role of DNA damage and repair in radiation cancer therapy: a current update and a look to the futureSemantic proximity Read ↗

Coordination of DNA Mismatch Repair and Base Excision Repair Processing of Chemotherapy and Radiation Damage for Targeting Resistant CancersSemantic proximity Read ↗

Molecular Targets and Mechanisms of Radiosensitization Using DNA Damage Response PathwaysSemantic proximity Read ↗

Targeting DNA Replication Stress for Cancer TherapySemantic proximity Read ↗

Molecular targets that sensitize cancer to radiation killing: From the bench to the bedsideSemantic proximity Read ↗

DNA damage response signaling pathways and targets for radiotherapy sensitization in cancerSemantic proximity Read ↗

Targeting DNA Double-Strand Break (DSB) Repair to Counteract Tumor Radio-resistanceSemantic proximity Read ↗

Combined Radiations: Biological Effects of Mixed Exposures Across the Radiation SpectrumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.