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Article

Genetic structure and contrasting selection pattern at two major histocompatibility complex genes in wild house mouse populations.

Heredity - 1 May 2011

Cížková D, Gouy de Bellocq J, Baird S J E, Piálek J, Bryja J

Abstract excerpt

The mammalian major histocompatibility complex (MHC) is a tightly linked cluster of immune genes, and is often thought of as inherited as a unit. This has led to the hope that studying a single MHC gene will reveal patterns of evolution representative of the MHC as a whole. In this study we analyse a 1000-km transect of MHC variation traversing the European house mouse hybrid zone to compare signals of selection...

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Identifiers

PMID: 20823902
DOI: 10.1038/hdy.2010.112
PMCID: PMC3186229

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Source receipt: pubmed, retrieved 7 Sept 2026.

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