Article
Evolution of MHC-DRB class II polymorphism in the genus Apodemus and a comparison of DRB sequences within the family Muridae (Mammalia: Rodentia).
Immunogenetics - 1 Sept 2004
Musolf Kerstin, Meyer-Lucht Yvonne, Sommer Simone
Abstract excerpt
Allelic diversity at major histocompatibility complex (MHC) genes is thought to be maintained by balancing selection over long periods of time, even across multiple speciation events. Trans-species sharing of MHC alleles among genera has been supported by many studies on mammals and fish, but in rodents, the results are ambiguous. We investigated natural levels of MHC- DRB variability and evolutionary processes...
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