Article
HLA-G 14 bp deletion/insertion polymorphism in celiac disease.
The American journal of gastroenterology - 1 Jan 2011
Fabris Annalisa, Segat Ludovica, Catamo Eulalia, Morgutti Marcello, Vendramin Anna, Crovella Sergio
Abstract excerpt
OBJECTIVES: Nonclassical major histocompatibility class I HLA-G antigen is a tolerogenic molecule that inhibits lytic activity of natural killer (NK) cells and cytotoxic T lymphocytes. Because of its immunomodulatory and tolerogenic properties, HLA-G molecules may have a role in celiac disease (CD). We analyzed the HLA-G 14 bp deletion/insertion polymorphism, known to have a functional effect on mRNA stability,...
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