Article
Selection and transformation of non-beta-lactamase-mediated insusceptibility to beta-lactams in Haemophilus influenzae: lack of cross-resistance between carbapenems and other agents.
The Journal of antimicrobial chemotherapy - 1 Dec 1990
Powell M, Livermore D M
Abstract excerpt
Non-beta-lactamase-mediated insusceptibility to beta-lactams was studied in Haemophilus influenzae. Mutants resistant to ampicillin were selected in a susceptible isolate, while phenotypically similar resistance was transformed from four wild-type isolates into a susceptible recipient. Ampicillin...
Topics
- Ampicillin Resistance
- Carbapenems
- Cross Reactions
- DNA, Bacterial
- Drug Resistance, Microbial
- Haemophilus influenzae
- Microbial Sensitivity Tests
- Mutation
- Plasmids
- Transformation, Bacterial
- beta-Lactamases