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Characterization of macrolide resistance genes in Haemophilus influenzae isolated from children with cystic fibrosis

16 Nov 2010

Abstract excerpt

OBJECTIVES: to determine the mechanism(s) of macrolide resistance in Haemophilus influenzae isolated from cystic fibrosis (CF) patients participating in a randomized placebo-controlled trial of azithromycin. METHODS: macrolide susceptibility, mutations and carriage of the macrolide resistance genes erm(A), erm(B), erm(C), erm(F) and mef(A) were determined using PCR assays and sequencing or hybridization of the...

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PMID: 21081549
DOI: 10.1093/jac/dkq425

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