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A new future of forensic Y-chromosome analysis: rapidly mutating Y-STRs for differentiating male relatives and paternal lineages.

Forensic science international. Genetics - 1 Mar 2012

Ballantyne Kaye N, Keerl Victoria, Wollstein Andreas, Choi Ying, Zuniga Sofia B, Ralf Arwin, Vermeulen Mark, de Knijff Peter, Kayser Manfred

Abstract excerpt

The panels of 9-17 Y-chromosomal short tandem repeats (Y-STRs) currently used in forensic genetics have adequate resolution of different paternal lineages in many human populations, but have lower abilities to separate paternal lineages in populations expressing low Y-chromosome diversity. Moreover, current Y-STR sets usually fail to differentiate between related males who belong to the same paternal lineage and,...

Topics

Alleles
Chromosomes, Human, Y
DNA Fingerprinting
Genetic Linkage
Genotype
Haplotypes
Humans
Male
Microsatellite Repeats
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multiplex Polymerase Chain Reaction

Mutation

Pedigree

Source

Identifiers

PMID: 21612995
DOI: 10.1016/j.fsigen.2011.04.017

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