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Article

Signaling pathways in renal cell carcinoma.

Cancer biology & therapy - 1 Oct 2010

Banumathy Gowrishankar, Cairns Paul

Abstract excerpt

Renal cell carcinoma (RCC), the most lethal type of genitourinary cancer, is generally resistant to chemotherapy and radiation therapy. Surgical excision of the tumor at a localized stage remains the mainstay for curative therapy. A number of drugs developed in recent years have shown limited to significant efficacy in treating RCC. These drugs act by blocking critical signaling pathways associated with RCC tumor...

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Share to Antineoplastic Agents
Share to Carcinoma, Renal Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neovascularization, Pathologic

Share to Receptors, Vascular Endothelial Growth Factor

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Source

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Identifiers

PMID: 20814228
DOI: 10.4161/cbt.10.7.13247
PMCID: PMC3093809

Genes

HGF
MET
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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