Article
Association of a Notch 3 gene polymorphism with migraine susceptibility.
Cephalalgia : an international journal of headache - 1 Feb 2011
Menon S, Cox H C, Kuwahata M, Quinlan S, MacMillan J C, Haupt L M, Lea R A, Griffiths L R
Abstract excerpt
INTRODUCTION: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) shares common symptoms with migraine. Most CADASIL causative mutations occur in exons 3 and 4 of the Notch 3 gene. This study investigated the role of C381T (rs 3815188) and G684A (rs 1043994) single nucleotide polymorphisms (SNP) in exons 3 and 4, respectively, of the Notch 3 gene in migraine....
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