Article
Mutation screening and association analysis of NOTCH3 p.R544C in patients with migraine with or without aura.
Cephalalgia : an international journal of headache - 1 Aug 2022
Wang Yen-Feng, Liao Yi-Chu, Tzeng Yi-Shiang, Chen Shih-Pin, Lirng Jiing-Feng, Fuh Jong-Ling, Chen Wei-Ta, Lai Kuan-Lin, Lee Yi-Chung, Wang Shuu-Jiun
Abstract excerpt
BACKGROUND: The role of the NOTCH3 p.R544C variant, the predominant variant of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in multiple East Asian regions, in migraine is unknown. METHODS: Migraine patients (n = 2,884) (2,279F/605M, mean age 38.8 ± 11.7 years), including 324 (11.2%) with migraine with aura, were prospectively enrolled by headache specialists according...
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