Article
Angiotensin-converting enzyme gene polymorphism and respiratory muscle function in infants.
Pediatric pulmonology - 1 Dec 2010
Dimitriou Gabriel, Papakonstantinou Despina, Stavrou Eleana F, Tzifas Sotirios, Vervenioti Aggeliki, Athanassiadou Aglaia, Mantagos Stefanos
Abstract excerpt
OBJECTIVE: Angiotensin-converting enzyme (ACE) gene contains a polymorphism consisting of either the presence (I) or absence (D) of a 287-bp fragment. Recent studies have suggested that the I-allele may be associated with superior exercise endurance; respiratory muscle function may be similarly influenced. The pressure-time index of inspiratory muscles (PTImus) is a measure of the load-capacity ratio of the...
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