Article
Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target.
The Journal of clinical endocrinology and metabolism - 1 Dec 2010
Marlow Laura A, D'Innocenzi Jaclyn, Zhang Yilin, Rohl Stephen D, Cooper Simon J, Sebo Thomas, Grant Clive, McIver Bryan, Kasperbauer Jan L, Wadsworth J Trad, Casler John D, Kennedy Pamela W, Highsmith W Edward, Clark Orlo, Milosevic Dragana, Netzel Brian, Cradic Kendall, Arora Shilpi, Beaudry Christian, Grebe Stefan K, Silverberg Marc L, Azorsa David O, Smallridge Robert C, Copland John A
Abstract excerpt
CONTEXT: Anaplastic thyroid carcinoma (ATC) is a highly aggressive carcinoma in need of therapeutic options. One critical component of drug discovery is the availability of well-characterized cell lines for identification of molecular mechanisms related to tumor biology and drug responsiveness. U...
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