Maternal alcohol consumption, alcohol metabolism genes, and the risk of oral clefts: a population-based case-control study in Norway, 1996-2001.

doi:10.1093/aje/kwq226

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Article

Maternal alcohol consumption, alcohol metabolism genes, and the risk of oral clefts: a population-based case-control study in Norway, 1996-2001.

American journal of epidemiology - 15 Oct 2010

Boyles Abee L, DeRoo Lisa A, Lie Rolv T, Taylor Jack A, Jugessur Astanand, Murray Jeffrey C, Wilcox Allen J

Abstract excerpt

Heavy maternal alcohol consumption during early pregnancy increases the risk of oral clefts, but little is known about how genetic variation in alcohol metabolism affects this association. Variants in the alcohol dehydrogenase 1C (ADH1C) gene may modify the association between alcohol and clefts. In a population-based case-control study carried out in Norway (1996-2001), the authors examined the association...

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PMID: 20810466
DOI: 10.1093/aje/kwq226
PMCID: PMC2984244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.