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Article

Striatal dopamine function in a family with multiple SCA-3 phenotypes.

Journal of neurology - 1 Feb 2011

Cubo Esther, López Mateo Diez, Ceberio Jon Infante, Alfonso Isabel Lanchas, Martinez Begoña Miguel, Berciano José, Iglesias Fernando, Obeso José A

Abstract excerpt

We present single photon emission computed tomography (SPECT) studies using 123IFP-CIT (DAT scan) and 123I-IBZM imaging, performed on four members of a family with genetically proven spinocerebellar ataxia type 3 (SCA-3). DAT scan showed significant asymmetric decreased binding in the striatum in the two members with predominant parkinsonian phenotype, with mild and symmetric decreased binding in the member with...

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PMID: 20809346
DOI: 10.1007/s00415-010-5724-z

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CIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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