Dopaminergic response in Parkinsonian phenotype of Machado-Joseph disease.

Abstract excerpt

We report on a patient with genetically proven Machado-Joseph Disease (MJD) presenting with signs indistinguishable from Parkinson's disease (PD), including levodopa response and typical levodopa-induced motor fluctuations. Only after 10 years of prolonged benefit from levodopa and different dopamine agonists (DA), the patient developed cerebellar ataxia and pyramidal signs. Preferential D3-receptor-stimulating...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Basal Ganglia
• Share to Contrast Media
• Share to Dopamine Agonists