Article
Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2, a new unstable variant occurring in low quantities.
Hemoglobin - 1 Jan 1990
Harkness M, Harkness D R, Kutlar F, Kutlar A, Wilson J B, Webber B B, Codrington J F, Huisman T H
Abstract excerpt
A severe hemolytic anemia with microcytosis and hypochromia was present in a young adopted Indian patient. Reversed phase high performance liquid chromatographic methodology and heat stability tests detected an unstable alpha chain which was present in 3 to 5% of the total hemoglobin. A larger qu...
Topics
- Amino Acid Sequence
- Anemia, Hemolytic, Congenital
- Base Sequence
- Child, Preschool
- Hemoglobins, Abnormal
- Humans
- India
- Male
- Molecular Sequence Data
- Mutation
- Restriction Mapping