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Article

Hb Southern Italy: coexistence of two missence mutations (the Hb Sun Prairie alpha2 130 Ala --> Pro and Hb Caserta alpha2 26 Ala --> Thr) in a single HBA2 gene.

British journal of haematology - 1 Oct 2008

Passarello Cristina, Giambona Antonino, Prossomariti Luciano, Ammirabile Massimiliano, Pucci Piero, Renda Disma, Pagano Leonilde, Maggio Aurelio

Abstract excerpt

This study describes a new molecular condition in the alpha(2)-globin gene (HBA2) found in six unrelated families from Southern Italy (Campania and Sicily). This new double mutant form of haemoglobin is called Hb Southern Italy and originated from the coexistence of two known mutations occurring in the same globin gene, HBA2 26 G-->A (Hb Caserta) and HBA2 130 G-->C (Hb Sun Prairie). Hb Sun Prairie was originally...

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Source

Identifiers

PMID: 18691171
DOI: 10.1111/j.1365-2141.2008.07319.x

Genes

HBA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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