Article
Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Mar 1990
O'Hara B, Johann S V, Klinger H P, Blair D G, Rubinson H, Dunn K J, Sass P, Vitek S M, Robins T
Abstract excerpt
Gibbon ape leukemia virus (GALV) enters cells following interaction with a specific receptor protein. We have isolated human complementary DNAs (cDNAs) encoding a protein which, when expressed in normally uninfectable mouse NIH3T3 cells, confers on these cells specific sensitivity to infection by...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA
- Fibroblasts
- Genes
- Genetic Predisposition to Disease
- Humans
- Mammals
- Mice
- Molecular Sequence Data
- Protein Conformation
- Receptors, Virus
- Recombinant Proteins