Article
Characterization of a human gene conferring sensitivity to infection by gibbon ape leukemia virus.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Mar 1990
O'Hara B, Johann S V, Klinger H P, Blair D G, Rubinson H, Dunn K J, Sass P, Vitek S M, Robins T
Abstract excerpt
Gibbon ape leukemia virus (GALV) enters cells following interaction with a specific receptor protein. We have isolated human complementary DNAs (cDNAs) encoding a protein which, when expressed in normally uninfectable mouse NIH3T3 cells, confers on these cells specific sensitivity to infection by GALV. This was done by transfection into mouse cells of human DNA and selection of putative receptor gene...
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