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From skin cells to hepatocytes: advances in application of iPS cell technology

25 Aug 2010

Abstract excerpt

The discovery several years ago that fibroblasts and other somatic cells from mice and humans can be reprogrammed to become inducible pluripotent stem (iPS) cells has created enthusiasm for their potential applications in regenerative medicine and for modeling human diseases. Two independent studies in this issue of the JCI provide evidence that iPS cells represent a promising source of hepatocytes for a wide...

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PMID: 20739747
DOI: 10.1172/jci44422

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