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Induced pluripotent stem cells: From Nobel Prizes to clinical applications

3 Nov 2012

Abstract excerpt

Advances in basic hepatology have been constrained for many years by the inability to culture primary hepatocytes in vitro, until just over five years ago when the scientific playing field was changed beyond recognition with the demonstration that human skin fibroblasts could be reprogrammed to resemble embryonic cells. The reprogrammed cells, known as induced pluripotent stem cells (iPSCs), were then shown to...

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PMID: 23131523
DOI: 10.1016/j.jhep.2012.10.026

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