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Article

Human skin fibroblasts: From mesodermal to hepatocyte-like differentiation.

Hepatology (Baltimore, Md.) - 1 Nov 2007

Lysy Philippe A, Smets Françoise, Sibille Catherine, Najimi Mustapha, Sokal Etienne M

Abstract excerpt

The phenotypic homology of fibroblasts and mesenchymal stem cells (MSCs) has been recently described. Our study investigated the in vitro potential of human skin fibroblasts to differentiate into mesodermal (osteocyte and adipocyte) and endodermal (hepatocyte) cell lineages by comparison with human bone marrow (hBM) MSCs. The endodermal potential of fibroblasts was then explored in vivo in a mouse model of liver...

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PMID: 17969047
DOI: 10.1002/hep.21839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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