Article
Effect of hydroxyapatite and beta-tricalcium phosphate nanoparticles on promonocytic U937 cells.
Journal of biomedical nanotechnology - 1 Apr 2010
Jeanne Sylvie, Sylvie Jeanne, Tricot-Doleux Sylvie, Sylvie Tricot-Doleux, Pellen-Mussi Pascal, Pascal Pellen-Mussi, Perez Fabienne, Fabienne Perez, Oudadesse Hassane, Hassane Oudadesse, Cathelineau Guy, Guy Cathelineau
Abstract excerpt
OBJECTIVES: Nanoparticles from implanted materials are reported as the main cause of implant failure. Monocytes are among the first cells to colonize the inflammatory site. We evaluated the biological effects of bone substitutes presented to U937 cells in vitro as micron- or nanometer-sized particles. METHODS: The HA (550 nm) and beta-TCP (550 nm) nanoparticles were incubated with U937 cells. Cell cycle...
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