Article

A novel cell-free method to culture <i>Schistosoma mansoni</i> from cercariae to juvenile worm stages for <i>in vitro</i> drug testing

2018-06-07

Abstract excerpt

<h4>Background</h4> The arsenal in anthelminthic treatment against schistosomiasis is limited and relies almost exclusively on a single drug, praziquantel (PZQ). Thus, resistance to PZQ could constitute a major threat. Even though PZQ is potent in killing adult worms, it has been shown to be limited in its activity against earlier developmental stages. Current in vitro screening strategies for new drugs depend o...

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Literature Corpus work: ddb1c08f-fd9c-5af3-93cd-43e0833febec
DOI: 10.1101/341669

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