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Article

Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas.

Oncogene - 25 Nov 2010

Hadfield K D, Smith M J, Urquhart J E, Wallace A J, Bowers N L, King A T, Rutherford S A, Trump D, Newman W G, Evans D G

Abstract excerpt

Biallelic inactivation of the NF2 gene occurs in the majority of schwannomas. This usually involves a combination of a point mutation or multiexon deletion, in conjunction with either a second point mutation or loss of heterozygosity (LOH). We have performed DNA sequence and dosage analysis of th...

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Source

Identifiers

PMID: 20729918
DOI: 10.1038/onc.2010.363

Genes

SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20729918-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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