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Article

Posttranscriptional mechanisms account for differences in steady state levels of insulin receptor messenger RNA in different cells.

Molecular endocrinology (Baltimore, Md.) - 1 May 1991

Tewari M, Tewari D S, Taub R

Abstract excerpt

Previous studies have indicated that, in general, the insulin receptor gene is expressed at a level in cells reflecting the level of insulin receptors on the cellular surface. For instance, insulin-responsive tissues, such as hepatocytes, express high levels of both insulin receptor protein and mRNA relative to less responsive cells, such as fibroblasts. Moreover, in the cells of a patient (Minn1) with severe...

Topics

Alleles
Animals
Cell Line
Fibroblasts
Humans
Insulin
Kidney
Liver
Liver Neoplasms, Experimental
Lymphocytes
Promoter Regions, Genetic
RNA Processing, Post-Transcriptional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Receptor, Insulin

Source

Identifiers

PMID: 2072925
DOI: 10.1210/mend-5-5-653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2072925-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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