Article
[Congenital thrombocytopathies].
Der Internist - 1 Sept 2010
Kirchmaier C M, Pillitteri D
Abstract excerpt
Inherited thrombocytopathies are much less frequent in comparison to acquired platelet function disorders. However, congenital disorders can lead to severe bleeding tendency and are often not diagnosed. They are induced by different platelet defects based on disorders of platelet adhesion, receptors, secretion and signal transduction. In some cases they are associated with thrombocytopenia, giant platelets and...
Topics
- Bernard-Soulier Syndrome
- Blood Platelet Disorders
- Blood Platelets
- Diagnosis, Differential
- Genotype
- Hemorrhagic Disorders
- Humans
- Mass Screening
- Platelet Aggregation
- Platelet Function Tests
- Platelet Storage Pool Deficiency
- Prostaglandin-Endoperoxide Synthases
- Receptors, Collagen
- Thrombasthenia
- Thromboxane-A Synthase