Article
Analysis of human CD36 gene sequence alterations in the oxidized low-density lipoprotein-binding region using denaturing high-performance liquid chromatography.
Genetic testing and molecular biomarkers - 1 Aug 2010
Rać Monika Ewa, Suchy Janina, Kurzawski Grzegorz, Safranow Krzysztof, Jakubowska Katarzyna, Olszewska Maria, Garanty-Bogacka Barbara, Rać Michał, Poncyljusz Wojciech, Chlubek Dariusz
Abstract excerpt
Denaturing high-performance liquid chromatography (DHPLC) has been employed as a prescreening tool to reduce the amount of DNA sequencing. It could be a simple and cost-effective screening method for mutations and polymorphisms in exons 4, 5, and 6 of the CD36 gene, which encode the protein region responsible for the removal of oxidized low-density lipoprotein. Genomic DNA was isolated from 306 Caucasian infants...
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