Article
Olfaction in Parkin single and compound heterozygotes in a cohort of young onset Parkinson's disease patients.
Acta neurologica Scandinavica - 1 Oct 2016
Malek N, Swallow D M A, Grosset K A, Lawton M A, Smith C R, Bajaj N P, Barker R A, Ben-Shlomo Y, Bresner C, Burn D J, Foltynie T, Morris H R, Williams N, Wood N W, Grosset D G
Abstract excerpt
BACKGROUND: Parkin related Parkinson's disease (PD) is differentiated from idiopathic PD by absent or sparse Lewy bodies, and preserved olfaction. The significance of single Parkin mutations in the pathogenesis of PD is debated. OBJECTIVES: To assess olfaction results according to Parkin mutation status. To compare the prevalence of Parkin single heterozygous mutations in patients diagnosed with PD to the rate in...
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