Article
Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control.
Blood - 23 Apr 2009
Ferre April L, Hunt Peter W, Critchfield J William, Young Delandy H, Morris Megan M, Garcia Juan C, Pollard Richard B, Yee Hal F, Martin Jeffrey N, Deeks Steven G, Shacklett Barbara L
Abstract excerpt
There exists a unique group of persons who are able to durably control HIV in the absence of therapy. The mechanisms of control in these persons remain poorly defined. In this study, we examined CD8(+) T-cell responses in blood and rectal mucosa from 17 "elite controllers" (viral load < 75 copies/mL), 11 "viremic controllers" (75-2000 copies/mL), 14 noncontrollers (> 10,000 copies/mL), and 10...
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