Article
A nuclear mutation reversing a biased transmission of yeast mitochondrial DNA.
Genetics - 1 Jun 1991
Zweifel S G, Fangman W L
Abstract excerpt
The highly biased transmission of p- mitochondrial DNA that occurs in hypersuppressive matings between p- and p+ cells of the yeast Saccharomyces cerevisiae is thought to be a consequence of the replication advantage of the p- mtDNA. A nuclear gene, MGT1, that is required for this displacement of p+ mtDNA from zygotic clones has been identified through mutation. When one haploid parent carries the mgt1 allele,...
Topics
- Cell Nucleus
- Chromosomes, Fungal
- Crosses, Genetic
- DNA Replication
- DNA, Fungal
- DNA, Mitochondrial
- Gene Expression
- Genes, Fungal
- Genes, Recessive
- Mutation
- Saccharomyces cerevisiae