Article
Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.
Urology - 1 Oct 2010
Wang Baojun, Zhang Guoxi, Ouyang Jinzhi, Deng Xiyuan, Shi Taoping, Ma Xin, Li Hongzhao, Ju Zhenghua, Wang Chao, Wu Zhun, Liu Shuanglin, Zhang Xu
Abstract excerpt
OBJECTIVES: Hypertension often persists after adrenalectomy for primary aldosteronism. Traditional factors associated with postoperative hypertension were evaluated, but whether genetic determinants were involved remains poorly understood. The aim of this study was to investigate the association of DNA polymorphisms within steroid synthesis genes (CYP11B2, CYP11B1) and the postoperative resolution of hypertension...
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