Article
Gene expression profiling in skeletal muscle of Holstein-Friesian bulls with single-nucleotide polymorphism in the myostatin gene 5'-flanking region.
Journal of applied genetics - 1 Jan 2008
Sadkowski Tomasz, Jank Michał, Zwierzchowski Lech, Siadkowska Eulalia, Oprzadek Jolanta, Motyl Tomasz
Abstract excerpt
Myostatin (GDF-8) is a key protein responsible for skeletal muscle growth and development, thus mutations in the mstn gene can have major economic and breeding consequences. The aim of the present study was to investigate myostatin gene expression and transcriptional profile in skeletal muscle of Holstein-Friesian (Black-and-White) bulls carrying a polymorphism in the 5'-flanking region of the mstn gene (G/C...
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