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Article

Fine analysis of spontaneous MAGE-C1/CT7–specific immunity in melanoma patients

9 Aug 2010

Abstract excerpt

Cancer/testis (CT) antigens represent prime candidates for immunotherapy in cancer patients, because their expression is restricted to cancer cells and germ cells of the testis. MAGE-C1/CT7 is a CT antigen that is highly expressed in several types of cancers. Spontaneous occurrence of CT7-specific antibodies was previously detected by SEREX screen in a melanoma patient. However, naturally occurring CT7-specific...

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PMID: 20696919
DOI: 10.1073/pnas.1002155107

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