Article
Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16.
The Journal of biological chemistry - 12 Nov 2010
Weinitschke Sonja, Hollemeyer Klaus, Kusian Bernhard, Bowien Botho, Smits Theo H M, Cook Alasdair M
Abstract excerpt
Bacterial degradation of sulfoacetate, a widespread natural product, proceeds via sulfoacetaldehyde and requires a considerable initial energy input. Whereas the fate of sulfoacetaldehyde in Cupriavidus necator (Ralstonia eutropha) H16 is known, the pathway from sulfoacetate to sulfoacetaldehyde is not. The genome sequence of the organism enabled us to hypothesize that the inducible pathway, which initiates sau...
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