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Article

Heat shock protein polymorphism predisposes to urinary tract malformations and renal transplantation in children.

Transplantation proceedings - 1 Jan 2000

Rusai K, Banki N F, Prokai A, Podracka L, Szebeni B, Tulassay T, Reusz G S, Sallay P, Körmendy R, Szabo A J, Fekete A

Abstract excerpt

BACKGROUND: Anatomical malformations of the kidney and urinary tract account for 17% of pediatric renal transplantation procedures. Heat shock proteins (HSPs) are molecular chaperones with a protective function that promotes cell survival. HSP72 is an endogenous ligand for toll-like receptor TLR4, thereby stimulating innate immunity. Both in adults and children, decreased expression of HSP70s is associated with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20692469
DOI: 10.1016/j.transproceed.2010.05.010

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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