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Article

[Thrombotic-thrombocytopenic purpura].

Der Internist - 1 Sept 2010

Hellmann M, Hallek M, Scharrer I

Abstract excerpt

Thrombotic-thrombocytopenic purpura (TTP) is a microangiopathic disorder characterized by multiple von Willebrand-Factor (vWF) rich microthrombi affecting the arterioles and capillary vessels of several organs. Ultra large von Willebrand multimers cause the blood clotting process by linking to platelets due to a lack of a plasma metalloprotease named ADAMTS13. Deficiency of this vWF-cleaving enzyme is caused by...

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Topics

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Share to Antibodies, Monoclonal, Murine-Derived
Share to Immunologic Factors
Share to Plasma Exchange

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to ADAMTS13 Protein

Share to Purpura, Thrombotic Thrombocytopenic

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Source

Identifiers

PMID: 20689903
DOI: 10.1007/s00108-010-2599-0

Genes

ADAMTS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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