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Article

[Thrombotic thrombocytopenic purpura in childhood].

Hamostaseologie - 1 Feb 2004

Hassenpflug W-A, Angerhaus D, Budde U, Obser T, Schneppenheim R

Abstract excerpt

Thrombotic thrombocytopenic purpura (TTP) is a micro-angiopathic disease due to deficiency of the specific VWF cleaving protease (VWF-CP) ADAMTS13. The acquired form is caused by autoantibodies against VWF-CP, whereas mutations of the ADAMTS13 gene are responsible for inherited TTP. In childhood both forms exist with predominance of inherited TTP. The phenotype of TTP in childhood can be rather variable. Besides...

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Source

Identifiers

PMID: 15029276
DOI: 10.1267/hamo04010071

Genes

VWF
ADAMTS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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