Article
DMDM: domain mapping of disease mutations.
Bioinformatics (Oxford, England) - 1 Oct 2010
Peterson Thomas A, Adadey Asa, Santana-Cruz Ivette, Sun Yanan, Winder Andrew, Kann Maricel G
Abstract excerpt
UNLABELLED: Domain mapping of disease mutations (DMDM) is a database in which each disease mutation can be displayed by its gene, protein or domain location. DMDM provides a unique domain-level view where all human coding mutations are mapped on the protein domain. To build DMDM, all human proteins were aligned to a database of conserved protein domains using a Hidden Markov Model-based sequence alignment tool...
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