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Whole blood-derived miRNA profiles as potential new tools for ovarian cancer screening

1 Aug 2010

Abstract excerpt

BACKGROUND: Screening is an unsolved problem for ovarian cancer (OvCA). As late detection is equivalent to poor prognosis, we analysed whether OvCA patients show diagnostically meaningful microRNA (miRNA) patterns in blood cells. METHODS: Blood-borne whole miRNome profiles from 24 patients with OvCA and 15 age- and sex-matched healthy controls were biostatistically evaluated. RESULTS: Student's t-test revealed...

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PMID: 20683447
DOI: 10.1038/sj.bjc.6605833

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