Article
Beyond circulating microRNA biomarkers: Urinary microRNAs in ovarian and breast cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2017
Gasparri Maria Luisa, Casorelli Assunta, Bardhi Erlisa, Besharat Aris Raad, Savone Delia, Ruscito Ilary, Farooqi Ammad Ahmad, Papadia Andrea, Mueller Michael David, Ferretti Elisabetta, Benedetti Panici Pierluigi
Abstract excerpt
Breast cancer is the most common malignancy in women worldwide, and ovarian cancer is the most lethal gynecological malignancy. Women carrying a BRCA1/2 mutation have a very high lifetime risk of developing breast and ovarian cancer. The only effective risk-reducing strategy in BRCA-mutated women is a prophylactic surgery with bilateral mastectomy and bilateral salpingo-oophorectomy. However, many women are...
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