Article
Validation of blood testing for K-ras mutations in colorectal and pancreatic cancer.
Anticancer research - 1 Jul 2010
Rogosnitzky Moshe, Danks Rachel
Abstract excerpt
BACKGROUND: K-ras mutation in a tumour is a powerful negative predictor for treatment success. Identifying tumour K-ras mutation is complex, and could be simplified by an appropriate blood test. Clinical studies were identified in which K-ras mutation status was assessed in both blood and tumour to ascertain whether blood K-ras mutation is predictive of tumour K-ras mutation. Between 29% and 100% of patients with...
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