Article
RAS testing of colorectal carcinoma—a guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Group.
Journal of clinical pathology - 1 Sept 2014
Wong Newton A C S, Gonzalez David, Salto-Tellez Manuel, Butler Rachel, Diaz-Cano Salvador J, Ilyas Mohammad, Newman William, Shaw Emily, Taniere Philippe, Walsh Shaun V
Abstract excerpt
Analysis of colorectal carcinoma (CRC) tissue for KRAS codon 12 or 13 mutations to guide use of anti-epidermal growth factor receptor (EGFR) therapy is now considered mandatory in the UK. The scope of this practice has been recently extended because of data indicating that NRAS mutations and addi...
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