Article
[The association of hepatitis B virus genotype and the basal core promoter mutation in Qidong, China].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jul 2010
Jin Yan, Zhu Yu, Chen Tao-yang, Guo Xia, Zhang Jing, Wang Jin-bing, Chen Wei-zhong, Qian Geng-sun, Tu Hong
Abstract excerpt
OBJECTIVES: To investigate the prevalence of hepatitis B virus (HBV) genotypes and the association with hepatocellular carcinoma (HCC) or basal core promoter (BCP) mutation in Qidong, China. METHODS: The whole genome of HBV or X gene sequences were obtained from serum samples of HBV infected patients by using PCR and direct sequencing methods. Phylogenetic tree was constructed to determine the genotypes or...
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