Article
Evidence for linkage of the bladder exstrophy-epispadias complex on chromosome 4q31.21-22 and 19q13.31-41 from a consanguineous Iranian family.
Birth defects research. Part A, Clinical and molecular teratology - 1 Sept 2010
Reutter Heiko, Rüschendorf Franz, Mattheisen Manuel, Draaken Markus, Bartels Enrika, Hübner Norbert, Hoffmann Per, Payabvash Seyedmedhi, Saar Kathrin, Nöthen Markus M, Kajbafzadeh Abdol-Mohammad, Ludwig Michael
Abstract excerpt
BACKGROUND: The bladder exstrophy-epispadias complex (BEEC) is a spectrum of anomalies involving the abdominal wall, pelvis, urinary tract, genitalia, and, occasionally, the spine and anus. Although BEEC typically occurs sporadically, families with two or more affected members have been reported. The present authors previously conducted a genome-wide linkage analysis in two multiply affected (multiplex) families...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.