Article
Hereditary hemochromatosis (HFE) genotypes in heart failure: relation to etiology and prognosis.
BMC medical genetics - 29 Jul 2010
Møller Daniel V, Pecini Redi, Gustafsson Finn, Hassager Christian, Hedley Paula, Jespersgaard Cathrine, Torp-Pedersen Christian, Christiansen Michael, Køber Lars V
Abstract excerpt
BACKGROUND: It is believed that hereditary hemochromatosis (HH) might play a role in cardiac disease (heart failure (HF) and ischemia). Mutations within several genes are HH-associated, the most common being the HFE gene. In a large cohort of HF patients, we sought to determine the etiological role and the prognostic significance of HFE genotypes. METHODS: We studied 667 HF patients (72.7% men) with depressed...
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