Article
Hereditary hemochromatosis gene (HFE) mutations C282Y, H63D and S65C in patients with idiopathic dilated cardiomyopathy.
European journal of heart failure - 1 Jan 2005
Hannuksela Jokke, Leppilampi Mari, Peuhkurinen Keijo, Kärkkäinen Satu, Saastamoinen Eija, Heliö Tiina, Kaartinen Maija, Nieminen Markku S, Nieminen Pentti, Parkkila Seppo
Abstract excerpt
BACKGROUND: Hereditary hemochromatosis (HH), a common autosomal recessive disease, leads to excessive iron accumulation in some organs, including the heart. It is therefore not surprising that cardiomyopathy is one of the most severe complications of HH. The HFE gene defects have been thought to contribute to idiopathic dilated cardiomyopathy (IDCM) in some patients, even though the results of genotype analyses...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.