Article

The pathogenicity of blood stream and central nervous system forms of Trypanosoma brucei rhodesiense trypanosomes in laboratory mice: a comparative study

2023-11-15

Abstract excerpt

<h4>Background: </h4> Human African trypanosomiasis (HAT) develops in two stages namely early stage when trypanosomes are found in the blood and late stage when trypanosomes are found in the central nervous system (CNS). The two environments are different with CNS environment reported as being hostile to the trypanosomes than the blood environment. The clinical symptoms manifested by the disease in the two environ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 53c3e612-79b2-50bb-b5e8-be8f80aa918f
DOI: 10.12688/f1000research.75518.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The pathogenicity of blood stream and central nervous system forms of Trypanosoma brucei rhodesiense trypanosomes in laboratory mice: a comparative studyDOI 10.12688/f1000research.75518.2Read

Phenotypic characteristics distinguishing bloodstream form and central nervous form of Trypanosoma brucei rhodesiense.Semantic proximity Read

Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hostsSemantic proximity Read

Focus–Specific Clinical Profiles in Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesienseSemantic proximity Read

From Invasion to Systemic Dysfunction: Pathophysiology of <em>Trypanosoma brucei</em> in Veterinary MedicineSemantic proximity Read

Isolation, cloning, and pathologic analysis of Trypanosoma evansi field isolatesSemantic proximity Read

Salivarian Trypanosomes Have Adopted Intricate Host-Pathogen Interaction Mechanisms That Ensure Survival in Plain Sight of the Adaptive Immune SystemSemantic proximity Read

The role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sicknessSemantic proximity Read

Murine Models for Trypanosoma brucei gambiense Disease Progression—From Silent to Chronic Infections and Early Brain TropismSemantic proximity Read

Atypical Human Infections by Animal TrypanosomesSemantic proximity Read

Study of Tissue Orientation and Parasite Load in Various Tissues and Blood in an Experimental Mouse Model of Acute ToxoplasmosisSemantic proximity Read

Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host SpeciesSemantic proximity Read

Blood signatures for second stage Human African Trypanosomiasis: A transcriptomic approach.Semantic proximity Read