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Article

A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.

Journal of cardiovascular electrophysiology - 1 Dec 2010

Laish-Farkash Avishag, Glikson Michael, Brass Dovrat, Marek-Yagel Dina, Pras Elon, Dascal Nathan, Antzelevitch Charles, Nof Eyal, Reznik Haya, Eldar Michael, Luria David

Abstract excerpt

OBJECTIVES: to conduct a clinical, genetic, and functional analysis of 3 unrelated families with familial sinus bradycardia (FSB). BACKGROUND: mutations in the hyperpolarization-activated nucleotide-gated channel (HCN4) are known to be associated with FSB. METHODS AND RESULTS: three males of Moro...

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Source

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Identifiers

PMID: 20662977
DOI: 10.1111/j.1540-8167.2010.01844.x
PMCID: PMC3005590

Genes

HCN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20662977-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.PMID 20662977Read ↗

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