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Article

DNA diagnosis of hydatidiform mole using the polymerase chain reaction.

Human genetics - 1 Jun 1991

Fukuyama R, Takata M, Kudoh J, Sakai K, Tamura S, Shimizu N

Abstract excerpt

We have used the polymerase chain reaction (PCR) technique for the diagnosis of hydatidiform mole, a trophoblastic disease. For this, we targeted the hypervariable 3' flanking region of the APOB gene (APOB/VNTR) because of its high heterozygosity index (0.61) in the Japanese population. We examined seven clinical cases which were tentatively diagnosed as hydatidiform moles. Five of these revealed DNA segments...

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PMID: 2066110
DOI: 10.1007/BF00204186

Genes

APOB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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