Article
Cell cycle-specific expression of the SWI4 transcription factor is required for the cell cycle regulation of HO transcription.
Genes & development - 1 Jul 1991
Breeden L, Mikesell G E
Abstract excerpt
Expression of the HO endonuclease triggers mating-type switching in Saccharomyces cerevisiae. Transcription of the HO gene is start-dependent and restricted to the late G1/early S phase of haploid mother cells. The HO promoter contains 10 copies of a cell cycle-regulated upstream activation sequence, which is activated by SWI4 and SWI6. SWI4 mRNA levels vary at least 10-fold throughout the cell cycle and rise...
Topics
- Cell Cycle
- DNA-Binding Proteins
- Deoxyribonucleases, Type II Site-Specific
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Mutation
- Promoter Regions, Genetic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors